Lysophospholipid Receptors: Signaling and Biochemistry by Jerold Chun,Timothy Hla,Sarah Spiegel,Wouter Moolenaar

By Jerold Chun,Timothy Hla,Sarah Spiegel,Wouter Moolenaar

The present kingdom of the technological know-how helping new examine in lysophospholipids

The examine of lysophospholipids exploded with the invention of telephone floor receptors on either lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). because then, millions of unique study reports—ranging from primary cellphone signaling to the body structure and pathophysiology of person organ systems—have based on lysophospholipids. This ebook attracts jointly and analyzes the present literature to supply readers with a state-of-the-science evaluate in addition to present recommendations that aid learn in all features of the sphere of lysophospholipid signaling.

Lysophospholipid Receptors is split into 3 sections:

  • Receptors and different attainable effectors
  • Enzymes
  • Physiology and pathophysiology

Within each one part, the authors clarify the similarities and changes among LPA and S1P signaling. Examples are only if reveal the underlying mechanisms of lysophospholipid signaling throughout a extensive diversity of organ platforms, reminiscent of S1P signaling in cardiovascular body structure and ailment and the neural results of LPA signaling. vast references on the finish of every bankruptcy supply a gateway to the literature and facilitate extra learn into person topics.

Each bankruptcy has been authored by way of a number of prime foreign gurus in lysophospholipid examine. in line with a radical research of the present learn, the authors set forth what's demonstrated technological know-how and provide their specialist opinion and point of view on new and rising parts of study, atmosphere the level for extra investigations that might clear up present difficulties within the field.

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